Project Three: MR Imaging of Failed Regeneration and Cardiopulmonary Function
|Glenn Walter, PhD, University of Florida
Krista Vandenborne, PT, PhD, University of Florida
Aim 1: Prospectively determine the association between LTBP4 polymorphisms and cardiac disease progression.
Aim 2: Examine the impact of LTBP4 IAAM haplotype on MR measures of respiratory muscles and loss of pulmonary function.
Aim 3: Retrospective study of the association between SPP1 and LTBP4 gene polymorphisms and disease progression in the lower extremity muscles in a large DMD cohort.